半岛bd体育手机客户端 说明
一般描述
Supplied as a trifluoroacetate salt.
A cell-permeable analog of the Stat3-SH2 domain-binding phospho-peptide (Cat. No. 573095) that contains a C-terminal membrane translocating sequence (MTS) and acts as a highly selective, potent blocker of Stat3 activation. Also suppresses constitutive Stat3-dependent Src transformation with no effect on Stat3-independent Ras transformation.
A cell-permeable analog of the Stat3-SH2 domain-binding phosphopeptide (Cat. No. 573095) that contains a C-terminal mts (membrane translocating sequence) and acts as a highly selective, potent blocker of Stat3 activation. Also suppresses constitutive Stat-3 dependent Src transformation with no effect on Stat-3 independent Ras transformation. The unphosphorylated inactive control peptide is also available under Cat. No. 573105.
包装
1, 5 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Cell permeable: yes
Primary Target
Blocker of Stat3 activation
Product does not compete with ATP.
Reversible: no
警告
Toxicity: Standard Handling (A)
序列
H-Pro-Tyr-(PO?H?)-Leu-Lys-Thr-Lys-Ala-Ala-Val-Leu-Leu-Pro-Val-Leu-Leu-Ala-Ala-Pro-OH
其他说明
Turkson, J., et al. 2001.J. Biol. Chem.276,45443.
Rojas, M., et al. 1998.Nat. Biotechnol.16,370.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C92H157N20O24P |
| 分子量 | 1958.32 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | lyophilized solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze desiccated (hygroscopic) |
| 颜色 | white |
| 溶解性 | water: 1 mg/mL |
| 运输 | ambient |
| 储存温度 | ?20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
