半岛bd体育手机客户端 说明
一般描述
A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6). May also act as a substrate for caspase-4 and caspase-5. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).
包装
1 mg in Glass bottle
5 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Primary Target
A fluorogenic substrate for caspase-9
Reversible: no
Cell permeable: no
警告
Toxicity: Standard Handling (A)
序列
Ac-Leu-Glu-His-Asp-AFC
外形
Supplied as a trifluoroacetate salt.
重悬
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Ito, A., et al. 1999.Biochim. Biophys. Acta1452,263.
Thornberry, N.A., and Lazebnik, Y. 1998.Science281,1312.
Thornberry, N.A., et al. 1997.J. Biol. Chem.272,17907.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C33H38F3N7O11 |
分子量 | 765.69 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze desiccated protect from light |
颜色 | white |
溶解性 | DMSO: 5 mg/mL |
荧光 | λex~400 nm λem~505 nm |
运输 | ambient |
储存温度 | ?20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich