trihydroxycholestanoic acid

半岛bd体育手机客户端 说明

一般描述

Trihydroxycholestanoic acid (THCA) is an oxidative metabolite of cholesterol and a precursor to bile acids. Very long-chain acyl-CoA synthetase (VLCS) associated with endoplasmic reticulum and peroxisomes activates THCA, the C27 bile acid intermediate.

应用

Trihydroxycholestanoic acid has been used as a sterol to test its reactivity with human mincle protein.

生化/生理作用

Trihydroxycholestanoic acid (THCA) and dihydroxycholestanoic (DHCA) accumulation is observed in Zellweger syndrome and cholestatic liver disease. The synthesis of (25R)-isomer of DHCA and THCA is favored by mitochondrial 27-hydroxylase.

包装

5 mL Amber Glass Screw Cap Vial (700070P-1mg)

基本信息

经验(实验)分子式	C27H46O5
分子量	450.65
NACRES	NA.25

半岛bd体育手机客户端 性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 1 mg (700070P-1mg)
manufacturer/tradename	Avanti Polar Lipids 700070P
运输	dry ice
储存温度	?20℃
InChI	1S/C27H46O5/c1-15(6-5-7-16(2)25(31)32)19-8-9-20-24-21(14-23(30)27(19,20)4)26(3)11-10-18(28)12-17(26)13-22(24)29/h15-24,28-30H,5-14H2,1-4H3,(H,31,32)/t15-,16?,17+,18-,19-,20+,21+,22-,23+,24+,26+,27-/m1/s1
InChI key	CNWPIIOQKZNXBB-VCVMUKOKSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	No data available
闪点(C)	No data available