Short Chain Fatty Acid Kit

半岛bd体育手机客户端 说明

一般描述

Short chain fatty acids (SCFAs) are saturated fatty acids with less than 6 carbons. SCFAs are produced in the gut by microbial fermentation of dietary fibers.(1) The most important and researched SCFAs are Acetate (Ac), propionate (Pr) and butyrate (Bu).(2) SCFAs are predominantly found in the colon and cross the intestinal epithelium to the blood stream. SCFAs were found to be beneficial and effective in prevention of obesity, Non-alcoholic fatty liver disease and insulin resistance.(3,4)

应用

SCFAs can serve in various applications including in vitro and in vivo administration to study the effect on immune system activation(5), protect epithelial cells from LPS penetration by tight junction formation induction(6), effect insulin secretion(7) and more. In these studies, SCFAs were administrated in vitro at the following concentration range Acetate 1-10mM, propionate and butyrate 0.1-1mM and in vivo Acetate, 70 mM; propionate, 30 mM; butyrate, 20 mM.

生化/生理作用

Role

• Regulate metabolism in the gut
• Indicators of gut health and inflammation
• Associated with gastrointestinal diseases such as IBS and other conditions such as obesity, colonic carcinogenesis, insulin sensitivity and ischemic stroke

半岛bd体育手机客户端 性质

质量水平	100
储存温度	?20℃

安全信息

象形图
警示用语：	Danger
危险声明	H314
预防措施声明	P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
危险分类	Eye Dam. 1 - Skin Corr. 1B
储存分类代码	8A - Combustible, corrosive hazardous materials
WGK	WGK 1