半岛bd体育手机客户端 说明
包装
1 mg in glass bottle
生化/生理作用
Purvalanol A is found to inhibit ABCG2 (ATP-binding cassette G2) transporterin vitro. It is also known to attenuate cellular Src kinase action and induce cell cycle arrest at the G2 to M phase transition.
Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor.
特点和优势
This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C19H25ClN6O |
分子量 | 388.89 |
MDL编号 | MFCD02179211 |
PubChem化学物质编号 | 24898543 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
质量水平 | 200 |
测定 | ≥98% (HPLC) |
形式 | powder |
溶解性 | methylene chloride: 50 mg/mL |
运输 | dry ice |
储存温度 | ?20℃ |
SMILES string | CC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1 |
InChI | 1S/C19H25ClN6O/c1-11(2)15(9-27)23-19-24-17(22-14-7-5-6-13(20)8-14)16-18(25-19)26(10-21-16)12(3)4/h5-8,10-12,15,27H,9H2,1-4H3,(H2,22,23,24,25)/t15-/m0/s1 |
InChI key | PMXCMJLOPOFPBT-HNNXBMFYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich