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Purvalanol A

品牌
Sigma-Aldrich
CAS
212844-53-6
货号
P4484
规格纯度
≥98% (HPLC), powder
价格
1674.67 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
212844-53-6
Purvalanol A
2-(1R-Isopropyl-2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine
NG-60
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

包装

1 mg in glass bottle

生化/生理作用

Purvalanol A is found to inhibit ABCG2 (ATP-binding cassette G2) transporterin vitro. It is also known to attenuate cellular Src kinase action and induce cell cycle arrest at the G2 to M phase transition.
Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor.

特点和优势

This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式 C19H25ClN6O
分子量 388.89
MDL编号 MFCD02179211
PubChem化学物质编号 24898543
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 200
测定 ≥98% (HPLC)
形式 powder
溶解性 methylene chloride: 50 mg/mL
运输 dry ice
储存温度 ?20℃
SMILES string CC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1
InChI 1S/C19H25ClN6O/c1-11(2)15(9-27)23-19-24-17(22-14-7-5-6-13(20)8-14)16-18(25-19)26(10-21-16)12(3)4/h5-8,10-12,15,27H,9H2,1-4H3,(H2,22,23,24,25)/t15-/m0/s1
InChI key PMXCMJLOPOFPBT-HNNXBMFYSA-N

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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