POVPC

半岛bd体育手机客户端 说明

一般描述

1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) is a derivative of oxidized Low density lipoprotein (oxLDL), a proinflammatory lipid present in atherosclerotic lesions.

应用

1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) has been used:

• to study its effects on endothelial function and vasodilation
• as a ligand for LRP6 in bone marrow mesenchymal stromal cells (MSCs)
• as a oxidized lipid to study if membrane status at different degrees of lipid peroxidation is involved in oxidative stress tolerance

生化/生理作用

1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) affects endothelial function by hindering activity of endothelial nitric oxide synthase and stimulating endothelial cell apoptosis. It is implicated in the development of atherosclerosis and it may be used as a potent therapeutic for atherosclerosis.

包装

5 mL Clear Glass Sealed Ampule (870606P-1mg)

基本信息

经验(实验)分子式	C29H56NO9P
分子量	593.73
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 1 mg (870606P-1mg)
manufacturer/tradename	Avanti Polar Lipids 870606P
运输	dry ice
储存温度	?20℃
SMILES string	[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCC([H])=O)=O)COC(CCCCCCCCCCCCCCC)=O)=O

安全信息

储存分类代码

13 - Non Combustible Solids