Human DPPIV / CD26 ELISA Kit

半岛bd体育手机客户端 说明

一般描述

The Human CD26 (also known as DPPIV) ELISA (Enzyme- Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CD26 in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Human CD26

应用

请参考Protocol了解详情。

生化/生理作用

Dipeptidyl peptidase 4 (DPPIV), also known as CD26 (cluster of differentiation 26), is localized on T- cell surface and interacts with adenosine deaminase (ADA), collagen and CD459. It plays a vital role in T cell co-stimulation, cell-to-cell adhesion, and in human immunodeficiency virus (HIV) infection. Deletion of the DPPIV gene alters carbohydrate metabolism which in turn leads to mental retardation and hypotonia. Abnormal expression of DPPIV is observed during liver regeneration, human cirrhosis and liver tumorigenesis. DPPIV level is reduced in serum of chronic obstructive pulmonary disease (COPD) patients, hence, this protein has potential as a serologic marker for screening COPD. DPP4 functions as a serine protease enzyme that catalyzes the cleavage of dipeptides from peptides containing proline or alanine residues. IL-13 induced DPPIV expression is upregulated in bronchial epithelial cells (BECs) and this expression might contribute to the development of asthmatic airway inflammation, cell proliferation and fibronectin (FN) production. This protein is a promising biomarker and therapeutic target for asthma.

其他说明

A sample Certificate of Analysis is available for this product.
Please type the wordsamplein the text box provided for lot number.

基本信息

NACRES

NA.32

半岛bd体育手机客户端 性质

species reactivity	human
包装	kit of 96 wells (12 strips x 8 wells)
technique(s)	ELISA: suitable capture ELISA: suitable
input	sample type urine sample type plasma sample type serum sample type cell culture supernatant(s)
assay range	inter-assay cv: <12% intra-assay cv: <10% sensitivity: 25 pg/mL standard curve range: 32.77-8000 pg/mL
detection method	colorimetric
运输	wet ice
储存温度	?20℃
Gene Information	human ... DPP4(1803)

组份列表

组份可单独销售

货号	组份
RABELADA	ELISA 1X Assay/Sample Diluent Buffer A (Item D1)
RABELADB	ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
RABSTOP3	ELISA Stop Solution (Item I)
RABTMB3	ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
RABWASH4	20X Wash Buffer (Item B)

安全信息

象形图
警示用语：	Warning
危险声明	H290
预防措施声明	P234 - P390
危险分类	Met. Corr. 1
储存分类代码	8A - Combustible, corrosive hazardous materials
WGK	WGK 3