Cyclotraxin-B trifluoroacetate salt

品牌

Sigma-Aldrich

CAS

1203586-72-4

货号

SML1769

包装型号

1 MG, ≥95% (HPLC)

规格纯度

≥95% (HPLC)

价格

3349.38 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

1203586-72-4
Cyclotraxin-B trifluoroacetate salt
L-Cysteinyl-L-asparaginyl-L-prolyl-L-methionylglycyl-L-tyrosyl-L-threonyl-L-lysyl-L-a-glutamylglycyl-L-cysteine, cyclic (1>11)-disulfide
CNPMGYTKEGC (Modifications: Disulfide bridge between 1-11)

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

包装

1 mg in glass bottle

生化/生理作用

Cyclotraxin-B is a potent and selective Trk B (BDNF/NT-3) receptor inhibitor. Cyclotraxin-B prevents receptor activation by BDNF without interfering with BDNF binding. Cyclotraxin-B has an IC₅₀value < 1 nM. In rodent studies Cyclotraxin-B, sometimes fused with tat-protein for increased brain permeability, has been shown to have anxiolytic properties, prevent cold hypersensitivity induced by BDNF, and to reduce cocaine self-administration.

基本信息

经验(实验)分子式	C₄₈H₇₃N₁₃O₁₇S₃· xC₂HF₃O₂
分子量	1200.37 (free base basis)

半岛bd体育手机客户端性质

质量水平	100
测定	≥95% (HPLC)
形式	film
颜色	colorless
运输	wet ice
储存温度	?20℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable