半岛bd体育手机客户端 说明
一般描述
Cholesteryl ester transfer protein (CETP) is present in normal human plasma and transfers neutral lipids from high density lipoproteins (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). CETP plays an important role in lipoprotein metabolism and influences the reverse cholesterol transport pathway.
特点和优势
Synthetic assay components support manipulation for MOA studies and SAR work. Unusually high signal-to-background with linearity. Assay components stable for up to 1 year. High DMSO tolerance.
适用性
Suitable for high-throughput screening (HTS), mechanism of action (MOA) studies, and structure-activity relationship (SAR) work in CETP sources.
原理
The CETP RP Activity Assay uses a proprietary substrate that enables the detection of CETP-mediated neutral lipid mass transfer. The method is useful for measuring CETP activity in recombinant protein (RP) or purified CETP samples and has a high DMSO tolerance. The transfer activity results in an increase in fluorescence intensity (λEx= 465 nm/λEm= 535 nm). With recombinant CETP as the CETP source, the assay is linear over a wide range of CETP concentrations and provides very high signal-to-background values. Typical Z factor: ～0.9
基本信息
| NACRES | NA.84 |
半岛bd体育手机客户端 性质
| 用途 | sufficient for 100 fluorometric tests |
| detection method | fluorometric |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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