campesterol-d6

半岛bd体育手机客户端 说明

一般描述

Campesterol-d6 is the deuterated form of campesterol. It is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure. It is not synthesized in mammanls and is diet derived

应用

Campesterol-d6 has been used as a deuterium-labeled internal standard in gas chromatography (GC)–triple quadrupole mass spectrometry and liquid chromatography-high resolution mass spectrometry (LC-HRMS).

生化/生理作用

Campesterol reduces the levels of chylomicron. The d6-campesterol along with d6-sitosterol and d6-cholesterol has been used in the transport blood-brain barrier studies in human brain endothelial hCMEC/D3 monolayer cells. Campesterol is a biomarker for tracking cholesterol synthesis and absorption. Campesterol like cholesterol is catabolized by intestinal microbes. It possess chemopreventive functionality prostate and breast tumors. Campesterol also has antiangiogenic property and may be useful in treating disorders related to angiogenesis.

包装

5 mL Amber Glass Screw Cap Vial (700092P-1mg)

基本信息

经验(实验)分子式	C28H42D6O
分子量	406.72
NACRES	NA.25

半岛bd体育手机客户端 性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 1 mg (700092P-1mg)
manufacturer/tradename	Avanti Polar Lipids 700092P
运输	dry ice
储存温度	?20℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable