Atto 610 maleimide

半岛bd体育手机客户端 说明

应用

Atto 610 belongs to a new generation of fluorescent labels invented by ATTO-TEC. The dye is designed for application in the area of life science, e.g. labeling of DNA, RNA or proteins. Characteristic features of the label are strong absorption, high fluorescence quantum yield, high photostability, good water solubility, and very little triplet formation. Atto 610 is a pH sensitive product. While practically stable up to pH 8.5, it slowly degrades at higher pH. Maleimides are well suited for coupling to thiol groups. This is similar to iodacetamides, but maleimides do react more thiol selective. They do not show significant reaction with histidine or methionine. Hydrolysis of maleimides to a mixture of isomeric nonreactive maleamic acids can compete significantly with thiol modification, particularly above pH 8. Maleimides may be used for labeling of amines, which usually requires a higher pH than reaction of maleimides with thiols.

法律信息

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

基本信息

经验(实验)分子式	C31H37ClN4O7
分子量	613.10
MDL编号	MFCD04040681
PubChem化学物质编号	57650025
NACRES	NA.32

半岛bd体育手机客户端 性质

质量水平	100
半岛bd体育手机客户端 线	BioReagent
测定	≥90% (coupling to thiols)
荧光	λex610 nm; λem637 nm in 0.1 M phosphate pH 7.0, 2-mercaptoethanol
适用性	suitable for fluorescence
储存温度	?20℃
SMILES string	[O-]Cl(=O)(=O)=O.C\[N+](C)=C1/C=CC2=Cc3cc4CCCN(CCCC(=O)NCCN5C(=O)C=CC5=O)c4cc3C(C)(C)C2=C1
InChI	1S/C31H36N4O3.ClHO4/c1-31(2)25-19-24(33(3)4)10-9-21(25)17-23-18-22-7-5-14-34(27(22)20-26(23)31)15-6-8-28(36)32-13-16-35-29(37)11-12-30(35)38;2-1(3,4)5/h9-12,17-20H,5-8,13-16H2,1-4H3;(H,2,3,4,5)
InChI key	NIZBDUMEZAIMFT-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)