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位置: 首页> 品牌> Sigma-Aldrich> 抗 大鼠 IgM(μ-链特异性)- 过氧化物酶 山羊抗

Anti-Rat IgM (μ-chain specific)-Peroxidase antibody produced in goat

抗 大鼠 IgM(μ-链特异性)- 过氧化物酶 山羊抗

品牌
Sigma-Aldrich
货号
SAB3700672
规格纯度
affinity isolated antibody, lyophilized powder
价格
4069.14 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Rat IgM (μ-chain specific)-Peroxidase antibody produced in goat
HRP
抗 大鼠 IgM(μ-链特异性)- 过氧化物酶 山羊抗
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Immunoglobulin M (IgM) exists as a pentamer in the serum and has a high molecular weight. Monomeric IgM has a molecular weight of 190kDa. The pentameric IgM consists of ten μ-heavy chains, ten light chains and a single J-chain which are linked by disulphide bonds. The μ-chain consists of five domains- VH, Cμ1, Cμ2, Cμ3 and Cμ4. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. They are known as Fragment antigen binding (Fab) fragments. The third fragment does not possess antigen-binding activity and is known as fragment crystallizable (Fc). It interacts with cells and effector molecules. The heavy chains of IgM contain an extra C domain that replaces the hinge region present between Fab and Fc. IgM is the first antibody to be produced during an immune response.

特异性

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Rat IgM coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Peroxidase, Anti-Goat Serum, Rat IgM and Rat Serum. Specificity was confirmed by ELISA at less than 1% cross reactivity against other Rat heavy or light chain isotypes.

免疫原

Rat IgM mu heavy chain

物理属性

Antibody format: IgG

外形

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

重悬

Reconstitute with 1.0 mL deionized water (or equivalent).

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.46

半岛bd体育手机客户端 性质

质量水平 100
生物来源 goat
偶联物 peroxidase conjugate
抗体形式 affinity isolated antibody
antibody product type secondary antibodies
克隆 polyclonal
形式 lyophilized powder
species reactivity rat
technique(s) immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
运输 wet ice
储存温度 2-8℃

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H317
预防措施声明 P280
危险分类 Skin Sens. 1
储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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