7α,27-dihydroxy-4-cholesten-3-one

半岛bd体育手机客户端 说明

一般描述

7α,27-dihydroxy-4-cholesten-3-one synthesized by the hydroxylation of 27-hydroxycholesterol in the presence of the enzyme cholesterol 7 α-hydroxylase (CYP7A1) and is catabolized to bile acid. 7α,27-dihydroxy-4-cholesten-3-one is present majorly in fibroblasts and its conversion from cholesterol occurs in extrahepatic tissues.

应用

7α,27-dihydroxy-4-cholesten-3-one may be used as a ligand to test its effect on Epstein-Barr virus-induced molecule 2 (EB12) activation in guanosine 5′-O-(3-thio)triphosphate ([³⁵S] GTPγS) binding assay.

生化/生理作用

7α,27-dihydroxy-4-cholesten-3-one is a suppressor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.

包装

5 mL Amber Glass Screw Cap Vial (700023P-1mg)

基本信息

经验(实验)分子式	C27H44O3
分子量	416.64

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 1 mg (700023P-1mg)
manufacturer/tradename	Avanti Polar Lipids 700023P
运输	dry ice
储存温度	?20℃

安全信息

储存分类代码

13 - Non Combustible Solids