4β-hydroxycholesterol-d7

半岛bd体育手机客户端 说明

一般描述

4β-hydroxycholesterol (4β-HC) is a catabolic product of cholesterol metabolism mediated by the enzyme cytochrome P450 family 3 subfamily A member 4 (CYP3A4). 4β-hydroxycholesterol-d7 is the deuterated form of 4β-hydroxycholesterol.

应用

4β-hydroxycholesterol-d7 has been used:

• as an internal standard to spike plasma samples ultra-high-pressure liquid,chromatography–tandem mass spectrometry (UHPLC-MS/MS) analysis
• to spike serum samples for mass spectrometry measurements
• as an internal standard for the quantification of human colon biopsies samples using HPLC-MS

生化/生理作用

4β-hydroxycholesterol (4β-HC) may function as a liver X receptor ligand. The levels of 4β-HC are elevated in dextran sulfate induced colitis along with other oxysterols and it may promote colon inflammation.

包装

5 mL Amber Glass Screw Cap Vial (700042P-1mg)

基本信息

经验(实验)分子式	C27H39O2D7
分子量	409.70
NACRES	NA.25

半岛bd体育手机客户端 性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 1 mg (700042P-1mg)
manufacturer/tradename	Avanti Polar Lipids 700042P
运输	dry ice
储存温度	?20℃

安全信息

储存分类代码

13 - Non Combustible Solids