16:0-06:0 NBD PS

半岛bd体育手机客户端 说明

一般描述

Phosphatidylserine (PS) is a membrane phospholipid enriched in the cytosolic leaflet of plasma membrane. It comprises 2-10% of total phospholipids. NBD PS is a flurosently labelled phospholipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.

应用

16:0-06:0 NBD PS or 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) has been used in the 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) ? phospholipase (PL) translocation assay to characterize an ATP-dependent flippase activity in yeast Golgi membranes. It may be used: to detect vesicular stomatitis virus G (VSV G) protein mediated cell-cell fusion, measure the enzyme substrate specificity of lipoteichoic acid (LTA) synthase (LtaS), in liposomes to determine the role of phospholipid scramblase 1 (PLSCR1) in phospholipid scrambling.
16:0-06:0 NBD PS has been used as a labelled translocase to detect ATP-dependent translocation across late Golgi membranes. It is also suitable for analysis of phospholipid scramblase 1 (PLSCR1) scrambling in proteoliposomes and to determine enzyme specificity of lipoteichoic acid synthase enzyme (LtaS).

生化/生理作用

Phosphatidylserine (PS) is involved in the regulation of many enzymes and structural components. It serves as an essential factor in the clearance of apoptotic cells. It is associated with cognitive disability in Alzheimer′s disease.

包装

5 mL Amber Glass Screw Cap Vial (810192P-1mg)

基本信息

经验(实验)分子式	C34H59N6O13P
分子量	790.84
NACRES	NA.25

半岛bd体育手机客户端 性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 1 mg (810192P-1mg)
manufacturer/tradename	Avanti Polar Lipids 810192P
运输	dry ice
储存温度	?20℃

安全信息

储存分类代码

13 - Non Combustible Solids