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Plasmin Inhibitor Screening Kit (Fluorometric)

纤溶酶抑制剂筛选试剂盒(荧光法)

品牌
Sigma-Aldrich
货号
MAK245
规格纯度
sufficient for 100 fluorometric tests
价格
6853.1 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Plasmin Inhibitor Screening Kit (Fluorometric)
纤溶酶抑制剂筛选试剂盒(荧光法)
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Plasmin (EC 3.4.21.7) is a serine protease occurring in plasma as plasminogen. Upon activation via cleavage by plasminogen activators; plasmin solubilizes fibrin clots and activates and/or degrades compounds of the coagulation and complement systems. Plasmin inhibitors are critical in the treatment of hyperfibrinolysis-associated with blood loss and other related complications. A number of biological processes including immune response, fibrinolysis, hemostasis and the elimination of inflammation are affected by serine protease inhibition. Snake venom is considered to be a source of many serine protease inhibitor.

适用性

Suitable for screening potential inhibitors of plasmin and characterizing/studying plasmin inhibitors in plasma samples.

原理

The Plasmin Inhibitor Screening Kit utilizes the ability of plasmin to cleave a synthetic AMC-based peptide substrate and release a fluorophore, AMC, which can be easily quantified by fluorescence microplate readers. In the presence of plasmin specific inhibitors, the extent of cleavage reaction is reduced or completely abolished. The loss in the fluorescence intensity can be correlated to the amount of inhibitor present in the assay solution. The kit provides a simple and rapid method to screen potential inhibitors of Plasmin.

基本信息

NACRES NA.25

半岛bd体育手机客户端 性质

detection method fluorometric
储存温度 ?20℃

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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