半岛bd体育手机客户端 说明

一般描述

This ELISA antibody pair detects mouse TNFSF4/OX40.

应用

请参考Protocol了解详情。

生化/生理作用

Tumor necrosis factor (TNF) superfamily member 4 (Tnfsf4) signals specifically through the OX40 receptor, which is expressed primarily on CD4⁺T cells but also on certain activated CD8⁺T cells. Tnfsf4 acts as a costimulatory signal, which is essential for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival and increases expression of regulated on activation, normal T cell expressed and secreted (RANTES) or chemokine ligand 5 (CCL5), interleukins-2 and -3 and interferon γ (IFNg). Tnfsf4 signaling plays an important role in immuno-regulatory communication and immune-tolerance. Polymorphisms in the TNFSF4 gene leads to the development of autoimmune thyroid diseases (AITDs), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and systemic sclerosis (SSc).

其他说明

A sample Certificate of Analysis is available for this product.
Please type the wordsamplein the text box provided for lot number.

半岛bd体育手机客户端 性质

species reactivity	mouse
包装	kit of 96 wells (12 strips x 8 wells)
technique(s)	ELISA: suitable
input	sample type serum sample type plasma sample type cell culture supernatant(s)
assay range	inter-assay cv: <10% intra-assay cv: <12% sensitivity: 30 pg/mL
detection method	colorimetric
运输	wet ice
储存温度	?20℃
Gene Information	mouse ... Tnfsf4(22164)

组份列表

组份可单独销售

货号	组份
RABTMB3	ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
RABSTOP3	ELISA Stop Solution (Item I)
RABELADA	ELISA 1X Assay/Sample Diluent Buffer A (Item D1)
RABELADB	ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
RABWASH4	20X Wash Buffer (Item B)

安全信息

象形图
警示用语：	Warning
危险声明	H290
预防措施声明	P234 - P390
危险分类	Met. Corr. 1
储存分类代码	8A - Combustible, corrosive hazardous materials
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable