半岛bd体育手机客户端 说明

一般描述

Gremlin-1 (GREM1) is part of the secreted, cysteine knot DAN family of bone morphogenetic protein antagonists. It has a molecular weight of 24–26kDa.

应用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生化/生理作用

Gremlin-1 (GREM1) has a role in embryogenesis. It also has a role in cell functions during development. GREM1 acts as an antagonist of bone morphogenetic proteins (BMP). The protein influences chondrogenesis, outgrowth and apoptosis in limb bud development and has a role in kidney formation. It inhibits the activity of BMP2 and BMP4. GREM1 is involved in angiogenesis, bone formation, bone mass and pulmonary hypertension. Knockout of this gene in mice leads to developmental abnormalities.

其他说明

A sample Certificate of Analysis is available for this product. Please type the wordsamplein the text box provided for lot number.

基本信息

NACRES

NA.32

半岛bd体育手机客户端 性质

species reactivity	mouse
包装	kit of 96 wells (12 strips x 8 wells)
technique(s)	ELISA: suitable
input	sample type plasma sample type serum sample(s) sample type cell culture supernatant(s)
assay range	inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.8 ng/ml
detection method	colorimetric
运输	wet ice
储存温度	?20℃
Gene Information	mouse ... Grem1(23892)

安全信息

象形图
警示用语：	Warning
危险声明	H290
预防措施声明	P234 - P390
危险分类	Met. Corr. 1
储存分类代码	8A - Combustible, corrosive hazardous materials
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable