C12-NBD Ceramide

半岛bd体育手机客户端 说明

应用

C12-NBD ceramide is suitable for its use:

• as a substrate to measure the activity of acid, alkaline and neutral ceramidases
• inin vitroceramidase activity assay
• in ceramide phosphoethanolamine (CPE) synthase assay to determine the K_mand V_maxof sphingomyelin synthase (SMS1, SMS2, and SMSr)

生化/生理作用

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthase family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

包装

5 mL Amber Glass Screw Cap Vial (810211C-1mg)

基本信息

经验(实验)分子式	C36H61N5O6
分子量	659.90
NACRES	NA.25

半岛bd体育手机客户端 性质

测定	>99% (TLC)
包装	pkg of 1 × 1 mL (810211C-1mg)
manufacturer/tradename	Avanti Polar Lipids 810211C
浓度	1 mg/mL (810211C-1mg)
运输	dry ice
储存温度	?20℃

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372
预防措施声明	P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
危险分类	Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官	Central nervous system
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	does not flash
闪点(C)	does not flash