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Biphalin trifluoroacetate salt

品牌
Sigma-Aldrich
CAS
126872-95-5
货号
SML0299
包装型号
规格纯度
≥97% (HPLC)
价格
3573.74 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
126872-95-5
Biphalin trifluoroacetate salt
L-Tyrosyl-D-alanylglycyl-L-phenylalanine 2-(L-tyrosyl-D-alanylglycyl-L-phenylalanyl)hydrazide
1,2-Bis(L-Tyr-D-Ala-Gly-L-Phe-)hydrazine
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

Amino Acid Sequence

(Tyr-DAla-Gly-Phe-NH)2

包装

1 mg in glass bottle

生化/生理作用

Biphalin is a dimeric enkephalin that is a potent and non-selective opioid receptors (OR) agonist. It displays a high analgesic potency that is over 1000-fold greater than morphine. Studies show that biphalin exhibits neuroprotective effects in rat models of stroke.
Biphalin trifluoroacetate salt, a highly active synthetic octapeptide, is an analog of biphalin. It displays a strong affinity in the nanomolar range for the receptors μ and δ.

特点和优势

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式 C46H56N10O10· xC2HF3O2
分子量 909.00 (free base basis)
MDL编号 MFCD23380198
PubChem化学物质编号 329825305
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥97% (HPLC)
形式 lyophilized solid
颜色 white to beige
运输 wet ice
储存温度 ?20℃
SMILES string OC(=O)C(F)(F)F.C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)NNC(=O)[C@H](Cc3ccccc3)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc4ccc(O)cc4
InChI 1S/C46H56N10O10.C2HF3O2/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32;3-2(4,5)1(6)7/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66);(H,6,7)/t27-,28-,35+,36+,37+,38+;/m1./s1
InChI key KNKVMVJCRGCBFW-GJLSYRFBSA-N

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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