半岛bd体育手机客户端 说明

一般描述

7β,25-dihydroxycholesterol (7β25OHC) is an isomer of 7α,25-dihydroxycholesterol (7α25OHC). Its synthesis from 7-keto,25-hydroxycholesterol (7k25OHC) is catalyzed by 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1). 11β-Hydroxysteroid dehydrogenase type 2 (11β-HSD2) catalyzes the reverse oxidation from 7β25OHC to 7k25OHC.

应用

7β,25-dihydroxycholesterol has been used as a substrate for 11β-Hydroxysteroid dehydrogenase (11β-HSD)-dependent metabolic studies of oxysterols in human embryonic kidney (HEK-293) cells in enzyme kinetics assay and as a standard in high-performance liquid chromatography(HPLC) for detection of dihydroxycholesterols in human plasma.

生化/生理作用

7β,25-dihydroxycholesterol is an Epstein-Barr virus-induced gene 2 (EBI2) ligand and is comparatively a weaker chemoattractant than 7α,25-dihydroxycholesterol (7α25OHC).

包装

5 mL Amber Glass Screw Cap Vial (700081P-1mg)

基本信息

经验(实验)分子式	C27H46O3
分子量	418.65
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 1 mg (700081P-1mg)
manufacturer/tradename	Avanti Polar Lipids 700081P
运输	dry ice
储存温度	?20℃
SMILES string	CC1(CC[C@H](O)C2)C2=C[C@H](O)C3C1CCC4(C)C3CCC4C(CCCC(C)(O)C)C

安全信息

储存分类代码

13 - Non Combustible Solids