7α,27-dihydroxycholesterol

半岛bd体育手机客户端 说明

一般描述

7α,27-dihydroxycholesterol (7α,27-di-OHC) is an oxysterol with oxidized side chains. 7α,27-dihydroxycholesterol (7α27-OHC) is synthesized by the hydroxylation of 27-Hydroxycholesterol (27-OHC) and is a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC).

生化/生理作用

7α,27-dihydroxycholesterol (7α,27-di-OHC) is one of the metabolite screened in pathological conditions such as neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome and diabetes by lipidomics analysis of human specimens. Upon the lipopolysaccharide activation, the levels of 7α,27-di-OHC decreases.7α27-OHC is a ligand for Epstein-Barr virus-induced gene 2 (EBI2).

包装

5 mL Amber Glass Screw Cap Vial (700024P-1mg)

基本信息

经验(实验)分子式	C27H46O3
分子量	418.65
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 1 mg (700024P-1mg)
manufacturer/tradename	Avanti Polar Lipids 700024P
运输	dry ice
储存温度	?20℃
InChI	1S/C27H46O3/c1-17(16-28)6-5-7-18(2)21-8-9-22-25-23(11-13-27(21,22)4)26(3)12-10-20(29)14-19(26)15-24(25)30/h15,17-18,20-25,28-30H,5-14,16H2,1-4H3/t17?,18-,20+,21-,22+,23+,24-,25+,26+,27-/m1/s1
InChI key	RXMHNAKZMGJANZ-DTTSCKGMSA-N

安全信息

储存分类代码

13 - Non Combustible Solids