您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> 7α,25-dihydroxycholesterol-d6

7α,25-dihydroxycholesterol-d6

品牌
Avanti
CAS
2260669-11-0
货号
700078P
规格纯度
7α,25-dihydroxycholesterol-d6, powder
价格
9080.45 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
2260669-11-0
7α,25-dihydroxycholesterol-d6
26,26,26,27,27,27-hexadeutero-7α,25-dihydroxycholesterol ; 111117
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

7α,25-dihydroxycholesterol (7α,25-OHC) is synthesized by the hydroxylation of cholesterol by the action of enzyme cholesterol 25-hydroxylase (CH25H) and cytochrome P450, family 7, subfamily b, polypeptide 1 (CYP7B1). The catabolic breakdown of 7α,25-OHC to bile acid precursors is catalyzed by the enzymes hydroxy-Δ-5-steroid dehydrogenase, 3β- and steroid Δ-isomerase 7 (HSD3B7). 7α,25-dihydroxycholesterol-d6 is the deuterated form of 7α,25-dihydroxycholesterol.

应用

7α,25-dihydroxycholesterol-d6 has be used as an internal standard in liquid chromatography electrospray ionization tandem mass spectrometric (LC–ESI-MS/MS) analysis of human plasma.

生化/生理作用

7α,25-dihydroxycholesterol (7α,25-OHC) serves as an endogenous ligand for G-protein-coupled receptor 183 (GPR183) or Epstein-Barr virus-induced gene 2 (EBI2). It plays a key role in the migration of type 3 innate lymphoid cells (ILC3) in the small intestine and colon. 7α,25-OHC mediates immune cell migration functionality by their chemoattractant property. Inhibition of 7α,25-OHC synthesis leads to impairment in the migration of B cells.

包装

5 mL Amber Glass Screw Cap Vial (700078P-1mg)

基本信息

经验(实验)分子式 C27H40D6O3
分子量 424.69
NACRES NA.25

半岛bd体育手机客户端 性质

测定 >99% (TLC)
形式 powder
包装 pkg of 1 × 1 mg (700078P-1mg)
manufacturer/tradename Avanti Polar Lipids 700078P
运输 dry ice
储存温度 ?20℃
SMILES string [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=C[C@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(O)(C([2H])([2H])[2H])C([2H])([2H])[2H]

安全信息

储存分类代码 13 - Non Combustible Solids
闪点(F) No data available
闪点(C) No data available

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map