17:0 Cyclic LPA

半岛bd体育手机客户端 说明

一般描述

Cyclic phosphatidic acid (cPA) is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). Thesn-2 hydroxy group of CPA forms a 5-membered ring with thesn-3 phosphate.

应用

17:0 Cyclic LPA or 1-heptadecanoyl-glycero-2,3-cyclic-phosphate (ammonium salt) has been used as an internal standard for the quantification of cyclic lysophosphatidic acid (LPA) esters in proton samples using reversed-phase ultra-performance liquid chromatography-tandem mass spectrometer (UPLC-MS/MS).

生化/生理作用

cPA affects numerous cellular functions, including anti-mitogenic regulation of the cell cycle, induction of stress fiber formation, inhibition of tumor cell invasion and metastasis, and regulation of differentiation and survival of neuronal cells.
Interestingly, many of these cellular responses caused by cPA oppose those of LPA despite the activation of apparently overlapping receptor populations.

包装

5 mL Amber Glass Screw Cap Vial (857324P-1mg)

基本信息

经验(实验)分子式	C20H42NO6P
分子量	423.52
NACRES	NA.25

半岛bd体育手机客户端 性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 1 mg (857324P-1mg)
manufacturer/tradename	Avanti Polar Lipids 857324P
运输	dry ice
储存温度	?20℃
SMILES string	O=P1([O-])O[C@H](COC(CCCCCCCCCCCCCCCC)=O)CO1.[NH4+]

安全信息

储存分类代码	13 - Non Combustible Solids
闪点(F)	No data available
闪点(C)	No data available