MTT-CAS 298-93-1-Calbiochem

半岛bd体育手机客户端 说明

一般描述

Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan. Spectrophotometric measurement of MTT-formazan at 540 or 570 nm allows quantitation of cell viability. Used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. An electron acceptor used for studying NADP-dependent dehydrogenases.

包装

1 g in Glass bottle
10 g in Plastic ampoule

生化/生理作用

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
Used as a direct indicator of cytotoxicity and apoptosis.

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

重悬

Following reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 1 month at -20°C.

其他说明

Liu, Y., et al. 1997.J. Neurochem.69,581.
Abdallah, M.A. 1980.Eur. J. Biochem.112,331.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C18H16BrN5S
分子量	414.32
MDL编号	MFCD00011964

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (silver nitrate titration)
形式	solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze
杂质	≤0.5% Sulfated ash
颜色	yellow
溶解性	PBS: 2 mg/mL
痕量阳离子	heavy metals: ≤0.001%
运输	ambient
储存温度	15-25℃
InChI	1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChI key	AZKSAVLVSZKNRD-UHFFFAOYSA-M

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335 - H341
预防措施声明	P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类	Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable