Monoamine Oxidase Insect Cell Control

半岛bd体育手机客户端 说明

一般描述

Monoamine oxidase is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs.

应用

Monoamine Oxidase inhibitors (MAOIs) are used to treat mental disorders including depression and Parkinson′s.
This product is suitable as a negative control for MAO-A and MAO-B.

生化/生理作用

Monoamine Oxidase (MAO) is an integral flavoprotein of the outer mitochondrial membrane. MAOs are responsible for catalyzing the oxidative deamination of a wide variety of xenobiotic and endobiotic primary, secondary, and tertiary amines. The primary endogenous function of MAOs involves the inactivation of monoamine neurotransmitters, such as serotonin and dopamine. MAOs exist in two isoforms, MAO-A and MAO-B, which share approximately 70% sequence identity on the amino acid level.1 Both isoforms are nearly ubiquitous in mammals, but show particularly high enzymatic activity in the central nervous system and liver.

基本信息

MDL编号	MFCD08705570
NACRES	NA.54

半岛bd体育手机客户端 性质

质量水平	200
重组	expressed in wild-type baculovirus infected BTI insect cells
测定	~2.5 mg per vial
形式	liquid
运输	dry ice
储存温度	?70℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)