半岛bd体育手机客户端 说明
一般描述
A potent, reversible, broad-range inhibitor of matrix metalloproteinases. Inhibits MMP-1 (IC50= 24 nM), MMP-3 (IC50= 18.4 nM), MMP-7 (IC50= 30 nM), and MMP-9 (IC50= 2.7 nM).
A potent, reversible, broad range inhibitor of matrix metalloproteinases. Inhibits MMP-1 (IC50= 24 nM), MMP-3 (IC50= 18.4 nM), MMP-7 (IC50= 30 nM), and MMP-9 (IC50= 2.7 nM).
包装
1 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Cell permeable: yes
Product does not compete with ATP.
Reversible: yes
Target IC50: 24 nM, 18.4 nM, 30 nM, 2.7 nM, against MMP-1, MMP-3, MMp-7, and MMP-9, respectively
警告
Toxicity: Standard Handling (A)
制备说明
Requires vigorous vortexing for 60 seconds to completely solubilize the product.
其他说明
Pikul, S., et al. 1998.J. Med. Chem.41,3568.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C21H27N3O8S2 |
| 分子量 | 513.58 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze |
| 颜色 | off-white |
| 溶解性 | DMSO: 100 mg/mL |
| 运输 | ambient |
| 储存温度 | ?20℃ |
| InChI | 1S/C21H27N3O8S2/c1-21(2)13-23(33(27,28)17-9-5-15(31-3)6-10-17)20(19(25)22-26)24(14-21)34(29,30)18-11-7-16(32-4)8-12-18/h5-12,20,26H,13-14H2,1-4H3,(H,22,25) |
| InChI key | MCSWSPNUKWMZHM-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
