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Mastoparan-7

品牌
Sigma-Aldrich
CAS
145854-59-7
货号
M212
规格纯度
≥97% (HPLC), lyophilized powder
价格
2428.75 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
145854-59-7
Mastoparan-7
Mas 7
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

Amino Acid Sequence

Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Ala-Leu-Leu-NH2

一般描述

Mastoparan-7 is an analog of the mastoparan peptide. It is present in the venom ofVespula lewisii. It was originally isolated from wasp venom.

应用

Mastoparan-7 has been used to study mastoparan-stimulated nucleotide binding to G proteins.

生化/生理作用

Mastoparan-7 (Mas-7) stimulates the G protein subunit Gαo/iby its mode of action (to bind to the plasma membrane). It possesses antiviral activity and is associated with histamine release from mast cells. It is also involved in the induction of potent mitochondrial permeability and tumor cell cytotoxicity.

分析说明

More potent analog of mastoparan.

基本信息

经验(实验)分子式 C67H124N18O15
分子量 1421.81
MDL编号 MFCD00144726
PubChem化学物质编号 329817929
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 200
测定 ≥97% (HPLC)
形式 lyophilized powder
储存温度 ?20℃
SMILES string CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O
InChI 1S/C67H124N18O15/c1-18-38(12)53(71)67(100)85-51(32-52(70)86)66(99)84-50(31-37(10)11)64(97)79-45(24-20-22-26-69)61(94)75-42(16)58(91)82-47(28-34(4)5)62(95)76-39(13)55(88)73-40(14)57(90)81-48(29-35(6)7)63(96)77-41(15)56(89)78-44(23-19-21-25-68)60(93)74-43(17)59(92)83-49(30-36(8)9)65(98)80-46(54(72)87)27-33(2)3/h33-51,53H,18-32,68-69,71H2,1-17H3,(H2,70,86)(H2,72,87)(H,73,88)(H,74,93)(H,75,94)(H,76,95)(H,77,96)(H,78,89)(H,79,97)(H,80,98)(H,81,90)(H,82,91)(H,83,92)(H,84,99)(H,85,100)/t38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,53-/m0/s1
InChI key HOLQXBRPSSZJMZ-FGRXCANLSA-N

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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