半岛bd体育手机客户端 说明
一般描述
A cell-permeable analog of CA-074 (Cat. No. 205530) that acts as an irreversible inhibitor of intracellular cathepsin B. Reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasionin vitro.
A cell-permeable analog of CA-074 (Cat. No. 205530) that acts as an irreversible inhibitor of intracellular cathepsin B.
包装
1 mg in Plastic ampoule
生化/生理作用
Cell permeable: yes
Primary Target
cathepsin B
Product does not compete with ATP.
Reversible: no
Target IC50: 2.24 nM against cathepsin B
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Sever, N., et al. 2002.Biol. Chem.383,839.
Authier, F., et al. 1999.J. Biol. Chem.274,33723.
Hill, P.A., et al. 1994.J. Cell Biochem.56,118.
Buttle, D.J., et al. 1992.Arch. Biochem. Biophys.299,377.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C19H31N3O6 |
| 分子量 | 397.47 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze |
| 颜色 | white |
| 溶解性 | DMSO: 10 mg/mL |
| 运输 | ambient |
| 储存温度 | ?20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
