Anti-phospho-APP (pThr⁶⁶⁸) antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

Amyloid precursor proteins (APPs) are transmembrane glycoproteins that are found in a wide range of tissues. APPs have 3 main isoforms, namely, APP695, APP751 and APP770 that are derived from alternative splicing events in cells. Accumulation of the cleavage products of APP, such as the β-amyloid peptide, can cause Alzheimer′s disease.
Rabbit Anti-phospho-APP (pThr⁶⁶⁸⁾antibody binds to human APP phosphorylated at Thr⁶⁶⁸. Mouse, rat and frog APP are 100% homologous.

免疫原

synthetic phosphopeptide corresponding to the region of APP containing threonine 688.

应用

Cultured cortical neurons were immunostained for APP using rabbit anti-phospho-APP (pThr688) antibody.
Rabbit Anti-phospho-APP (pThr⁶⁶⁸) antibody can be used for western blot applications at a dilution of 1:1,000.

外形

Solution in Dulbecco′s phosphate buffered saline (without Mg²⁺and Ca²⁺), pH 7.3, with 50% glycerol, 1.0 mg/mL BSA (IgG and protease free) and 0.05% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号

MFCD06798482

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	200
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	aqueous glycerol solution
用途	10 blots
分子量	antigen 100-140 kDa
species reactivity	human
technique(s)	western blot: 1:1000 using CAD cells transfected with wild type vs. T668A mutant APP.
UniProt登记号	P05067
储存温度	?20℃
Gene Information	human ... APP(351) mouse ... App(11820) rat ... App(54226)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable