Anti-Interleukin-11 antibody produced in goat

半岛bd体育手机客户端 说明

一般描述

Interleukin-11 (IL-11) is a pleotropic cytokine that belongs to the IL-6 family. The effects of IL-11 include hemopoiesis, macrophage differentiation and thrombopoiesis. Many cell types including osteoblasts, trophoblasts, fibroblasts, chondrocytes and a variety of tissue such as brain, gut, spinal cord and testis secrete IL-11. The cellular effects of IL-11 are mediated by a multimeric complex consisting of IL-11Rα and gp130Rβ subunits. The pathways activated by IL-11 include JAK/STAT, Ras/MAPK and Grb2 signaling. IL-11 plays a major role in inflammatory responses, immune responses by regulating the production of IgG by B cells and in tumorigenesis-related inflammation
Anti-Interleukin-11 antibody specifically reacts with human IL-11.

特异性

The antibody neutralizes the biological activity of recombinant human IL-11.

免疫原

recombinant human IL-11 expressed inSf21 insect cells.

应用

Anti-Human IL-11 is suitable for neutralization reactions.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

制备说明

Purified using protein G.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD00212981
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	goat
偶联物	unconjugated
抗体形式	IgG fraction of antiserum
antibody product type	primary antibodies
克隆	polyclonal
形式	lyophilized powder
species reactivity	human
technique(s)	neutralization: suitable
UniProt登记号	P20809
储存温度	?20℃
Gene Information	human ... IL11(3589)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)