Anti-Human IgG (Fc specific)-Peroxidase antibody, Mouse monoclonal

半岛bd体育手机客户端 说明

一般描述

Anti-Human IgG (Fc specific)-Peroxidase antibody, Mouse monoclonal (mouse IgG2a isotype) is derived from the HP-6017 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from a mouse immunized with purified human IgG myeloma proteins covalently coupled to poly aminostyrene (PAS) microbeads. IgGs (Immunoglobulin G) are the most common Immunoglobulin′s isotype in blood, lymph, cerebrospinal and peritoneal fluids and serve as key players in the humoral immune response. IgGs include four subclasses (IgG1, IgG2, IgG3, and IgG4), consist of a variable Fab fragment (which includes the antibody recognition site) and a conserved Fc fragment.

免疫原

Human IgG myeloma proteins

应用

Anti-Human IgG (Fc specific)-Peroxidase antibody has been used in enzyme linked immunosorbent assay (ELISA).

生化/生理作用

IgG (Immunoglobulin G) deficiencies are often associated with various diseases. The Fc fragment has various important functions (e.g complement fixation, site for rheumatoid factor attachment and protein A binding) which indicate on the importance of immunoreagents specific for the Fc fragment of Human IgG.

外形

Supplied as a lyophilized powder.

基本信息

NACRES

NA.46

半岛bd体育手机客户端 性质

质量水平	200
生物来源	mouse
偶联物	peroxidase conjugate
抗体形式	purified from hybridoma cell culture
antibody product type	primary antibodies
克隆	HP-6017, monoclonal
形式	lyophilized powder
species reactivity	human
浓度	~2 mg/mL
technique(s)	ELISA: 1:80,000-1:160,000 using 5 μg/mL Human IgG myeloma for coating
同位素/亚型	IgG2a
运输	dry ice
储存温度	?20℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable