p30

半岛bd体育手机客户端 说明

应用

p30 is an endogenous truncated form of p39 that associates with Cdk5 to form Nclk, which regulates neurotransmission, axon guidance, central nervous system (CNS) architecture, and pathogenesis. Therefore, p30 is useful in studying neurodegenerative diseases such as Alzheimer′s, Amyotrophic Lateral Sclerosis, and Parkinson′s Disease.

生化/生理作用

P30 activates GST-Neuronal cyclin-dependent kinase 5 (Cdk5). It also associates with Cdk5 to form an activated neuronal Cdc2-like kinase (Nclk). Product P1246 is recombinant, from bovine and is expressed inE. coli.

单位定义

One unit will incorporate 1 picomole of phosphate into histone H1 peptide per minute at pH 7.2 at 30 ℃.

外形

p30 is supplied in a solution of 25 mM Tris, pH 7.4, 1 mM DTT, and 30% glycerol. (0.5 μg protein/ 25 ul vial)

制备说明

Expressed as a GST fusion protein.

基本信息

MDL编号	MFCD01727216
PubChem化学物质编号	329820082
NACRES	NA.54

半岛bd体育手机客户端 性质

质量水平	200
形式	solution
储存温度	?20℃
SMILES string	Cl.CN(C)CCOc1ccc2OCCOc2c1
InChI	1S/C12H17NO3.ClH/c1-13(2)5-6-14-10-3-4-11-12(9-10)16-8-7-15-11;/h3-4,9H,5-8H2,1-2H3;1H
InChI key	VRCSNYKNBODDIM-UHFFFAOYSA-N