Monoclonal Anti-MRP3 antibody produced in mouse

半岛bd体育手机客户端 说明

一般描述

Multidrug Resistance-Associated Protein (MRP) is a seven member subfamily of ABC (ATP-binding cassette) transporters. MRP1, 2, and 3 have a similar structure with the ability to transport glutathione and glucuronate conjugates. MRP4 and MRP5 share more structure similarity with each other than with MRP1, 2, and 3. MRP4 and MRP5 also have the ability to transport cyclic nucleotides..The monoclonal anti-MRP3 recognizes human Multidrug Resistance-Associated Protein 3 (MRP3, 190-200 kDA)..

特异性

Reacts with an internal epitope of MRP3. Does not cross-react with the humanMDR1,MRP1,MRP2, orMRP5gene products.

免疫原

fusion protein of MRP3 (amino acids 830-949).

应用

The antibody may be used in immunocytochemistry, immunoblotting, immunohistochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

外形

Supplied in serum-free medium containing 0.7% bovine serum albumin and 0.1% sodium azide.

制备说明

Monoclonal Anti-Multidrug Resistance-Associated Protein 3 (MRP3), mouse isotype IgG1, derived using M₃II-21 hybridoma produced by fusion SP2/O mouse myeloma cells and Balb/c mouse lymph nodes cells immunized with amino acids 830-949 of the human MRP3 bacterial fusion protein. The antibody is concentrated from culture supernatant of M₃II-21 hybridoma cells grown in a bioreactor.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD02263753
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	200
生物来源	mouse
偶联物	unconjugated
抗体形式	tissue culture supernatant
antibody product type	primary antibodies
克隆	M3II-21, monoclonal
分子量	antigen 190-200 kDa
species reactivity	human
浓度	250 μg/mL
technique(s)	immunocytochemistry: 1:20-1:50 using acetone- or formaldehyde-fixed cytospin preparations immunohistochemistry (frozen sections): 1:20 using acetone-fixed sections western blot: 1:20-1:50
同位素/亚型	IgG1
UniProt登记号	O15438
运输	dry ice
储存温度	?20℃
Gene Information	human ... ABCC3(8714)

安全信息

储存分类代码

12 - Non Combustible Liquids