Monoclonal Anti-COX I antibody produced in mouse

半岛bd体育手机客户端 说明

免疫原

recombinant full length human COX I, 599 amino acids.

应用

Monoclonal Anti-COX I antibody produced in mouse is suitable for ELISA and western blotting. It was used to detect mitochondrial cytochrome c oxidase protein markerin homogenate and lipid droplet fractions isolated from L-cells by western blot analysis.

生化/生理作用

COX-I, an isoform of COX enzyme with 599 amino acid residues, catalyzes the conversion of arachinodate to prostaglandin H2. It is expressed mainly in the gut for the production of prostaglandins, which inhibit gastric secretion. It is involved in the regulation of homeostatic functions throughout the body, such as vascular hemostasis, renal blood flow, and maintenance of glomerular function. It is a target of NSAID (non-steroidal anti-inflammatory drugs) such as aspirin. COX-I can be induced by IL-β and other cytokines in monocytes, macrophages, and other cells as part of the inflammatory response.

外形

Solution in phosphate buffered saline, pH 7.4, containing 0.08% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD00217772
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	200
生物来源	mouse
偶联物	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	AS70, monoclonal
形式	buffered aqueous solution
species reactivity	human
浓度	1 mg/mL
technique(s)	indirect ELISA: suitable western blot: suitable
同位素/亚型	IgG1
UniProt登记号	P23219
运输	dry ice
储存温度	?20℃
Gene Information	human ... PTGS1(5742)