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Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)

品牌
Sigma-Aldrich
货号
764817
规格纯度
average Mn(1100-1000-1100), lactide:glycolide 75:25
价格
4229.44 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Poly(lactide- co-glycolide)- block-poly(ethylene glycol)- block-poly(lactide- co-glycolide)
PLGA-PEG-PLGA
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.

应用

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

包装

1 g in glass bottle

特点和优势

Biocompatible, degradable, thermosensitive, high stability, small size (<200 nm) and properties can be easily modified.

基本信息

NACRES NA.23

半岛bd体育手机客户端 性质

描述 typical PEG PDI<1.1; overall PDI≤2.0 (THF, PS)
质量水平 100
投料比 lactide:glycolide 75:25
分子量 PEG average Mn1,000
PLGA average Mn2,200
average Mn(1100-1000-1100)
降解时间线 2-3 weeks
转变温度 Tm230-235 ℃
PDI <2.0
储存温度 2-8℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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