半岛bd体育手机客户端 说明

一般描述

Diethyl (2-methylallyl)phosphonate is an organophosphorous compound. It participates in the synthesis of α-aminophosphonate derivatives and azaphosphones. The analgesic/antiinflammatory properties of these derivatives were evaluated.

应用

Diethyl (2-methylallyl)phosphonate can be used as a reagent in the Horner-Wadsworth-Emmons reaction to form conjugated carbon–carbon double bonds.
It can also be used as a reactant for:

• Enantioselective total synthesis of 10-isocyano-4-cadinene as antifouling agent.
• Regiospecific preparation of 4-oxo-2-alkenylphosphonates (OAP) via silylation followed by Friedel-Crafts acylation and isomerization. OAP can serve as building blocks for the construction of polyethylenic chains.
• The synthesis of azaphosphone as a potent analgesic/anti-inflammatory agents.

Reactant for:

• Enantioselective synthesis of 10-isocyano-4-cadinene and its stereoisomers with antifouling activity
• Preparation of 4-Oxo-2-alkenylphosphonates via silylation followed by regiospecific Friedel-Crafts acylation and isomerization

包装

1 g in glass bottle

基本信息

线性分子式	(C2H5O)2POCH2C(=CH2)CH3
分子量	192.19
MDL编号	MFCD05664300
PubChem化学物质编号	24881330
NACRES	NA.22

半岛bd体育手机客户端 性质

质量水平	100
测定	97%
reaction suitability	reaction type: C-C Bond Formation
折射率	n 20/D 1.4380 (lit.)
bp	62 ℃/0.1 mmHg (lit.)
密度	1.013 g/mL at 25 ℃ (lit.)
SMILES string	CCOP(=O)(CC(C)=C)OCC
InChI	1S/C8H17O3P/c1-5-10-12(9,11-6-2)7-8(3)4/h3,5-7H2,1-2,4H3
InChI key	QOZGSMHGXZMADD-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H319
预防措施声明	P305 + P351 + P338
危险分类	Eye Irrit. 2
储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	230.0 °F - closed cup
闪点(C)	> 110 ℃ - closed cup
个人防护装备	Eyeshields, Gloves, type ABEK (EN14387) respirator filter