半岛bd体育手机客户端 说明

应用

Microsomes from Liver, Pooled has been used to measure thein vitrostabilities of the prodrugs. It has also been used in microsomal incubation to generate BTX-3 metabolites to serve as references for liquid chromatography with tandem mass spectrometry (LC-MS/MS) analyses of urine.

生化/生理作用

Microsomal cytochrome P450 proteins can catalyze the transfer of a single oxygen atom to endogenous and exogenous compounds, like steroids and phenobarbital, meant for excretion and detoxification.
肝微粒体是来源于肝细胞内质网的亚细胞颗粒。这些微粒体是药物代谢酶(包括细胞色素 P-450)的丰富来源。不同来源的微粒体池有助于研究外源代谢和药物相互作用。

单位定义

One unit will produce 1.0 picomole of 6 beta-hydroxytestosterone per minute at pH 7.4 at 37 deg C.

半岛bd体育手机客户端 性质

质量水平	200
生物来源	Monkey (Cynomolgusspp.)
测定	~10 mg per vial
形式	liquid
specific activity	≥5000 units/mg protein
运输	dry ice
储存温度	?70℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable