Granzyme B Inhibitor II-CAS 1258003-96-1-Calbiochem

品牌

Sigma-Aldrich

CAS

1258003-96-1

货号

368055

包装型号

1 MG, The Granzyme B Inhibitor II, also referenced under CAS 1258003-96-1, controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

规格纯度

The Granzyme B Inhibitor II, also referenced under CAS 1258003-96-1, controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.

价格

1458.39 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

1258003-96-1
Granzyme B Inhibitor II-CAS 1258003-96-1-Calbiochem
Caspase-8 Inhibitor I, Ac-IETD-CHO

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

一般描述

Potent, reversible granzyme B and caspase-8 inhibitor.
A potent, reversible inhibitor of granzyme B and caspase-8 (K_i= 1 nM). Also inhibits caspase-1 (<6 nM), caspase-6 (5.6 nM), and caspase-10 (27 nM).

包装

1 mg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
Target K_i: 1 nM against caspase-8
Cell permeable: no
Reversible: yes

警告

Toxicity: Standard Handling (A)

序列

Ac-Ile-Glu-Thr-Asp-CHO

其他说明

Gao, C.F., et al. 2001.Exp. Cell. Res.265,145.
Garcia-Calvo, M., et al. 1998.J. Biol. Chem.273,32608.
Han, Z., et al. 1997.J. Biol. Chem.272,13422.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₂₁H₃₄N₄O₁₀
分子量	502.52

半岛bd体育手机客户端性质

质量水平	100
测定	≥95% (HPLC)
形式	lyophilized solid
manufacturer/tradename	Calbiochem^?
储存条件	OK to freeze
颜色	white
溶解性	DMSO: 1 mg/mL
运输	ambient
储存温度	?20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable