半岛bd体育手机客户端 说明
一般描述
A weak inhibitor of the human and murine granzyme B. Also inhibits the apoptosis-related DNA fragmentation in lymphocytes by fragmentin 2, a rat lymphocyte granule protease homologous to granzyme B (ID50= 300 nM).
A weak inhibitor of the human and murine serine protease granzyme B. Also inhibits the apoptosis related DNA fragmentation in lymphocytes by fragmentin 2, a rat lymphocyte granule protease homologous to granzyme B (ID50= 300 nM).
包装
1 mg in Plastic ampoule
生化/生理作用
Cell permeable: yes
Target IC50: 300 nM against the apoptosis-related DNA fragmentation in lymphocytes by fragmentin 2
Product does not compete with ATP.
Reversible: no
Primary Target
Granzyme B
警告
Toxicity: Standard Handling (A)
序列
Z-Ala-Ala-Asp-CH?Cl
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Gong, B., et al. 1999.Cell Growth Different.10,491.
Shi, L., et al. 1992.J. Exp. Med.176,1521.
Odake, S., et al. 1991.Biochemistry30,2217.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C19H24ClN3O7 |
| 分子量 | 441.86 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze desiccated |
| 颜色 | off-white |
| 溶解性 | DMSO: 5 mg/mL |
| 运输 | ambient |
| 储存温度 | ?20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
