半岛bd体育手机客户端 说明
一般描述
A cell-permeable, reversible inhibitor of γ-secretase. Inhibits the release of Aβx-40(ED50= 2.6 ?M) and Aβx-42(ED50= 2.7 ?M) in HEK293 cells stably transfected with Amyloid Precursor Protein Swedish mutants.
A cell-permeable, reversible inhibitor of γ-secretase. Equipotently inhibits the release of Aβx-40(ED50= 2.6 ?M) and Aβx-42(ED50= 2.7 ?M) in HEK293 cells stably transfected with the Amyloid Precursor Protein Swedish mutants.
包装
1 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Product does not compete with ATP.
Primary Target
Aβx-40
Reversible: yes
Cell permeable: yes
ED50 = 2.6 ?M for Aβx-40
警告
Toxicity: Standard Handling (A)
序列
2-Naphthoyl-Val-Phe-CHO
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Green, K.N., et al. 2002.J. Physiol.541.3,1013.
Sinha, S. and Lieberburg, I. 1999.Proc. Natl. Acad. Sci. USA96,11049.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C25H26N2O3 |
| 分子量 | 402.49 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | lyophilized solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze protect from light |
| 颜色 | white |
| 溶解性 | DMSO: 10 mg/mL |
| 运输 | ambient |
| 储存温度 | ?20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
