半岛bd体育手机客户端 说明
一般描述
A neutral glycosphingolipid (GSL) which is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco- series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase and c-fosexpression in human aortic smooth muscle cells.
Molecular weight: 960.4 (based on tricosanyl -23:0)
A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fosexpression in human aortic smooth muscle cells.
M.W. 960.4 (based on tricosanoyl - 23:0).
包装
1 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Reversible: no
Primary Target
A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL
Cell permeable: no
警告
Toxicity: Irritant (B)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
其他说明
Bhunia, A.K., et al. 1997.J. Biol. Chem.272,15642.
Bhunia, A.K., et al. 1996.J. Biol. Chem.271,10660.
Zacharias, C., et al. 1994.J. Biol. Chem.269,13313.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C53H101NO13 |
分子量 | 960.37 |
MDL编号 | MFCD00133445 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (TLC) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze |
颜色 | colorless |
溶解性 | ethanol: 1 mM methanol: 1 mM |
运输 | ambient |
储存温度 | ?20℃ |
InChI | 1S/C48H91NO13/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(53)49-36(37(52)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2)35-59-47-45(58)43(56)46(39(34-51)61-47)62-48-44(57)42(55)41(54)38(33-50)60-48/h29,31,36-39,41-48,50-52,54-58H,3-28,30,32-35H2,1-2H3,(H,49,53)/b31-29+/t36?,37?,38-,39-,41+,42+,43-,44-,45-,46+,47-,48?/m1/s1 |
InChI key | VOZHMDQUIRUFQW-AIRKALMMSA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich