半岛bd体育手机客户端 说明
一般描述
An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km= 0.426 ?M-1S-1), but not by Cathepsins B/L/S/F/H/V. Studies using WT and CatK-/-mice reveal that the substrate is not cleaved by other proteolytic enzymes present in fibroblast lysates. Emission Max: 420 NM, Excitation Max: 320 nM.
An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km= 0.426 ?M?? S??), but not by Cathepsins B/L/S/F/H/V.
An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km= 0.426 ?M-1S-1), but not by Cathepsins B/L/S/F/H/V. Studies using WT and CatK-/-mice reveal that the substrate is not cleaved by other proteolytic enzymes present in fibroblast lysates.
包装
1 mg in Plastic ampoule
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
序列
Abz-His-Pro-Gly~Gly-Pro-Gln-EDDnp
外形
Supplied as a trifluoroacetate salt.
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Lecaille, F., et al. 2003.Biochem. J.375,307.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C40H50N14O12 |
分子量 | 918.91 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze desiccated protect from light |
颜色 | bright yellow |
溶解性 | DMSO: 5 mg/mL |
荧光 | λex320 nm; λem420 nm |
运输 | wet ice |
储存温度 | ?20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich