Cathepsin Inhibitor III-Calbiochem

品牌

Sigma-Aldrich

货号

219419

包装型号

1 MG, The Cathepsin Inhibitor III controls the biological activity of Cathepsin. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

规格纯度

The Cathepsin Inhibitor III controls the biological activity of Cathepsin. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

价格

2340.22 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

Cathepsin Inhibitor III-Calbiochem
Z-FG-NHO-BzOME

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

一般描述

Cysteine protease inhibitor. Selectively inhibits cathepsin B (k₂/K_i= 1.0 x 10⁴M^-1sec^-1), cathepsin L (k₂/K_i= 1.5 x 10⁵M^-1sec^-1), cathepsin S (k₂/Ki= 6.6 x 10⁴M^-1sec^-1), and papain (k₂/K_i= 1.0 x 10³M^-1sec^-1). Half-life in buffered solution (pH 5-9) = 37 h (30°C); 300 h (0°C).
Cysteine protease inhibitor. Selectively inhibits cathepsin B (k₂/K_i= 1 x 10⁴M^-1sec^-1), cathepsin L (k₂/K_i= 1.5 x 10⁵M^-1sec^-1), cathepsin S (k₂/K_i= 6.6 x 10⁴M^-1sec^-1), and papain (k₂/K_i= 1 x 10³M^-1sec^-1).
Half-life in buffered solution (pH 5-9) = 37 h (30°C); 300 h (0°C).

包装

1 mg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
k?/K_i= 1 x 10? M?? sec??
Primary Target
cathepsin B
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

序列

Z-Phe-Gly-NHO-Bz-pOMe

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Demuth, H.-U., et al. 1996.Biochim. Biophys. Acta1295,179.
Br?mme, D., and Demuth, H.-U. 1994.Methods Enzymol.244,671.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₂₇H₂₇N₃O₇
分子量	505.52

半岛bd体育手机客户端性质

质量水平	100
测定	>90% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem^?
储存条件	OK to freeze desiccated protect from light
颜色	white
溶解性	ethanol: 1 mg/mL DMSO: 5 mg/mL
运输	ambient
储存温度	10-30℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable