半岛bd体育手机客户端 说明
一般描述
A potent inhibitor of IgE-mediated mast cell responses to allergensin vitroandin vivo. Also inhibits cyclin-dependent kinase 2 (Cdk2; IC50= 1 ?M) by blocking the ATP site.
A potent inhibitor of lgE-mediated mast cell responses to allergensin vitroandin vivo. Also inhibits cyclin-dependent kinase 2 (Cdk2; IC50= 1 ?M) by blocking the ATP site.
包装
1 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Target IC50: 1 ?M for Cdk2
Primary Target
Cdk2
Product does not compete with ATP.
Reversible: no
Cell permeable: no
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Shewchuk, L., et al. 2000.J. Med. Chem.43,133.
Chen, C.L., et al. 1999.Pharm. Res.16,117.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C16H15N3O3 |
| 分子量 | 297.31 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze protect from light |
| 颜色 | pale yellow |
| 溶解性 | DMSO: 50 mg/mL |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
