半岛bd体育手机客户端 说明

一般描述

A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (K_i= 300 nM). Inhibits protein kinase A (K_i= 21 ?M) and protein kinase C (K_i= 42 ?M) at much higher concentrations.
A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (K_i= 300 nM). Inhibits protein kinase A (K_i= 21 ?M)and protein kinase C (K_i= 42 ?M) at much higher concentrations.

包装

1 mg in Plastic ampoule

生化/生理作用

Cell permeable: yes
Product competes with ATP.
Target K_i: 300 nM against myosin light chain kinase
Primary Target
Myosin light chain kinase (Mlck)
Reversible: yes

警告

Toxicity: Standard Handling (A)

制备说明

Further dilute with aqueous buffer just prior to use.

重悬

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.

其他说明

Krarup, T., et al. 1998.Am. J. Physiol.275,C239.
Saitoh, M., et al. 1987.J. Biol. Chem.262,7796.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C15H17IN2O2S · xHCl
分子量	416.28 (free base basis)
MDL编号	MFCD00065524

半岛bd体育手机客户端 性质

质量水平	100
测定	>98% (TLC)
形式	solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze desiccated (hygroscopic) protect from light
颜色	white
溶解性	50% ethanol: 4.5 mg/mL DMSO: 4.5 mg/mL
运输	ambient
储存温度	2-8℃
InChI	1S/C15H17IN2O2S/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18/h1-2,4-7,17H,3,8-11H2
InChI key	GEHJIACZUFWBTK-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable