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Histone Deacetylase Inhibitor III

品牌
Sigma-Aldrich
CAS
251456-60-7
货号
382149
规格纯度
The Histone Deacetylase Inhibitor III, also referenced under CAS 251456-60-7, controls the biological activity of Histone Deacetylase. This small molecule/inhibitor is primarily used for Cell Structure applications.
价格
2287.32 *本价格含增值税费
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半岛bd体育手机客户端 名称:
251456-60-7
Histone Deacetylase Inhibitor III
M344, 4-Dimethylamino- N-(6-hydroxycarbamoylhexyl)benzamide, N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide
M344, 4-Dimethylamino- N-(6-hydroxycarbamoylhexyl)benzamide, N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A cell-permeable amide analog of Trichostatin A (Cat. No. 647925) that potently inhibits histone deacetylases (IC50= 40 nM for rat liver HDAC and IC50= 100 nM for maize HD). Induces differentiation and inhibits proliferation (~2 ?M) of murine erythroleukemia cells.
A cell-permeable, amide analog of Trichostatin A (Cat. No. 647925) that potently inhibits histone deacetylase (IC50= 40 nM for rat liver HDAC and IC50= 100 nM for maize HDAC). Induces differentiation and inhibits proliferation (~2 ?M) of murine erythroleukemia cells.

包装

1 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Primary Target
Rat liver HDAC
Product does not compete with ATP.
Reversible: no
Target IC50: 40 nM for rat liver HDAC

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Ramiszewski, S.W., et al. 2002.J. Med. Chem.45,753.
Jung, M., et al. 1999.J. Med. Chem.42, 4669.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C16H25N3O3
分子量 307.39
MDL编号 MFCD03453554

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 white
溶解性 DMSO: 1 mg/mL
运输 ambient
储存温度 ?20℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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