半岛bd体育手机客户端 说明
一般描述
A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II. Significantly more lipophilic and membrane-permeable than Rp-cGMPS or Rp-8-Br-cGMPS (Cat. No. 370674). Note: 1 ?mol = 0.61 mg.
A potent, cell-permeable inhibitor of protein kinase G Iα, Iβ, and type II. A combination of the protein kinase inhibitor Rp-cGMPS and the widely used cGMP analog, 8-pCPT-cGMP. Significantly more lipophilic and membrane-permeant than Rp-cGMPS and Rp-8-Br-cGMPS. Resistant to hydrolysis by mammalian cyclic nucleotide dependent phosphodiesterases. Note: 1 ?mol = 0.61 mg.
包装
1 μmol in Plastic ampoule
生化/生理作用
Cell permeable: yes
Primary Target
PKG1α
Product does not compete with ATP.
Reversible: no
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Abd Alla, S., et al. 1996.Eur. J. Biochem.241,498.
Lee, S.J., et al. 1996.Dev. Biol.180,324.
Van Uffelen, B.E., et al. 1996.J. Leukoc. Biol.60,94.
Willmott, N., et al. 1996.J. Biol. Chem.271,3699.
Butt, E., et al. 1994.Eur. J. Pharmacol.269,265.
法律信息
Sold under license of U.S. Patent 5,625,056, Patents DE 3,802,865.4, and DE 4,217,679 issued to BIOLOG LSI.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C16H15ClN5O6PS2· xC6H15N |
| 分子量 | 503.88 (free acid basis) |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥99% (HPLC) |
| 形式 | lyophilized |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze desiccated (hygroscopic) |
| 溶解性 | water: 0.5 mg/mL DMSO: soluble |
| 运输 | ambient |
| 储存温度 | ?20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
