半岛bd体育手机客户端 说明
一般描述
Potent inhibitor of cell adhesion. Inhibits tumor cell adhesion to laminin and vitronectin substrates.In vivoinvestigations in rats showed it to be useful in the amelioration of ischemic acute renal failure in rats. Also inhibits tubular obstruction by preventing cell-cell adhesion. Inhibits the redistribution of c-Src into focal adhesions, thereby leading to impaired MAP Kinase activation.
Potent inhibitor of cell adhesion. Inhibits tumor cell adhesion to laminin and vitronectin substrates.In vivoinvestigations showed it to be useful in the amelioration of ischemic acute renal failure in rats. Also inhibits tubular obstruction by preventing cell-cell adhesion.
包装
1 mg in Plastic ampoule
生化/生理作用
Primary Target
inhibits tumor cell adhesion to laminin and vitronectin substrates
Product does not compete with ATP.
Reversible: no
Cell permeable: no
警告
Toxicity: Standard Handling (A)
其他说明
Shono, T., et al. 2001.Exp. Cell Res.268,169.
Matsuno, H., et al. 1994.Circulation90,2203.
Noiri, E., et al. 1994.Kidney Int.46,1050.
Gurrath, M., et al. 1992.Eur. J. Biochem.210,911.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C26H38N8O7 |
分子量 | 574.63 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze desiccated (hygroscopic) |
颜色 | white |
溶解性 | 1 N acetic acid: 5 mg/mL |
运输 | ambient |
储存温度 | ?20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich