Monoclonal Anti-TFF3 antibody produced in mouse

半岛bd体育手机客户端 说明

一般描述

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. (provided by RefSeq)
They are secreted peptides that are protease-resistant. Trefoil factor-3 (TFF-3) is expressed in goblet cells.

免疫原

TFF3 (AAH17859.1, 15 a.a. ~ 73 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCFKPLQEAECTF

应用

Monoclonal Anti-TFF3 antibody produced in mouse has been used in immunohistochemistry.

生化/生理作用

Trefoil factor-3 (TFF-3) may be useful as a molecular marker for certain types of cancer, but its role in tumorigenesis is unknown. TFF3 promotes airway epithelial cell migration and differentiation.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
偶联物	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	3D9, monoclonal
形式	buffered aqueous solution
species reactivity	human
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable indirect ELISA: suitable western blot: 1-5 μg/mL
同位素/亚型	IgG1κ
GenBank?accession no.	BC017859
UniProt登记号	Q07654
运输	dry ice
储存温度	?20℃
Gene Information	human ... TFF3(7033)

安全信息

储存分类代码	12 - Non Combustible Liquids
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)